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Lidocaine hydrochloride

Lidocaine hydrochloride powder
CAS No: 73-78-9
Molecular Formula: C14H23ClN2O
Molecular Weight: 270.8g/mol
Purity: >99%
Appearance: White powder.
Transport Package: Aluminum Foil Bag or as Required
Usage: For Local Anesthetic


Description for Lidocaine hydrochloride


Lidoca hydrochloride is a local anesthetic and antiarrhythmic drug. Clinically, it is mainly used for infiltration anesthesia, epidural anesthesia, surface anesthesia (including mucosal anesthesia during thoracoscopy or abdominal surgery) and nerve conduction block. It can also be used for ventricular premature beats and ventricular tachycardia after acute myocardial infarction, as well as ventricular arrhythmias caused by digitalis poisoning, cardiac surgery and cardiac catheterization. But it is usually not effective for supraventricular arrhythmia. Lidoca hydrochloride is a local anesthetic of the amide type. After blood absorption or intravenous administration, it has obvious excitatory and inhibitory biphasic effect on the central nervous system, and there may be no pioneer excitement. When the blood Chemicalbook drug concentration is low, analgesia and drowsiness will appear, and the pain threshold will increase; with the dose Increasing, the effect or toxicity is enhanced, and there is anticonvulsant effect when the blood drug concentration is subtoxic; convulsions can occur when the blood drug concentration exceeds 5μg·ml-1. Lidocaine hydrochloride at low doses can promote K+ efflux in myocardial cells, reduce myocardial autonomy, and have anti-ventricular arrhythmia effects; at therapeutic doses, it can affect the electrical activity of myocardial cells, atrioventricular conduction and myocardial Contraction has no obvious effect; further increase in blood drug concentration can cause cardiac conduction velocity to slow, atrioventricular block, inhibit myocardial contractility and decrease cardiac output.


Lidocaine hydrochloride has the characteristics of strong penetrating, strong dispersibility, and fast onset. Its anesthetic efficacy is twice that of procaine, and its toxicity is 1. The anesthesia effect can appear 5 minutes after the medication, and the anesthesia effect can last for 1 to 1.5 hours, which is 50% longer than procaine. After absorption, it can inhibit the central nervous system, and can inhibit ventricular autonomy, shorten the Chemicalbook short refractory period, can be used to control ventricular tachycardia, treat ventricular premature beats, ventricular tachycardia and ventricular fibrillation and other arrhythmic symptoms. It is effective for heart disease or cardiac arrhythmia caused by cardiac glycosides, but it is not effective for supraventricular tachycardia. This product has a fast action, short duration, and is ineffective in oral administration. It is often administered as an intravenous injection.


Lidocaine                         CAS  137-58-6

Benzocaine                      CAS 94-09-7

Tetracaine                        CAS 94-24-6

Procaine                           CAS 59-46-1

Lidocaine hydrochloride   CAS 73-78-9

Tetracaine hydrochloride  CAS 136-47-0