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Tetracaine hydrochloride

Tetracaine hydrochloride powder
CAS No: 136-47-0
Molecular Formula: C15H25ClN2O2
Molecular Weight: 300.82g/mol
Purity: >99%
Appearance: White powder.
Transport Package: Aluminum Foil Bag or as Required
Usage: For Local Anesthetic


Description for Tetracaine hydrochloride


Tetracaine hydrochloride is a highly effective local anesthetic that reversibly blocks nerve function. It is clinically used for infiltration anesthesia, nerve block anesthesia, epidural anesthesia, etc. Compared with procaine, its local anesthetic effect is significant. It has been widely used clinically. Research on existing synthetic routes found that the synthesis of intermediate p-butylaminobenzoic acid is a key step in the synthesis of tetracaine hydrochloride, and Chemicalbook has always had the disadvantages of unstable raw materials or low yield in this step. Scientists have improved and perfected this. In 1981, it was proposed to synthesize p-butylaminobenzoic acid by the alkylation reaction of p-aminobenzoic acid and 1-bromobutane. However, the formation of dibutylated by-products cannot be avoided, and The nature of the raw material itself is unstable, making this route unsuitable for industrial production.


Tetracaine hydrochloride is a long-acting ester local anesthetic. Its characteristics are: strong penetration into mucosa, suitable for surface anesthesia, no adverse reactions such as vasoconstriction, dilated pupils, and corneal damage after instillation. It is often used in ophthalmology. Both local anesthesia and toxicity are approximately 10 times greater than that of procaine. After injection, anesthesia Chemicalbook's drunken effect appears slowly (about 10 minutes), and the metabolism after absorption is also slow. The local anesthesia time is up to 3IJ, H, -J. about. It is mainly used for surface anesthesia of the mucous membranes of the eyes, nose, and larynx. It is rarely used for conduction anesthesia and epidural anesthesia. Because of its high toxicity, it is generally not used for infiltration anesthesia.


Lidocaine                         CAS  137-58-6

Benzocaine                      CAS 94-09-7

Tetracaine                        CAS 94-24-6

Procaine                           CAS 59-46-1

Lidocaine hydrochloride   CAS 73-78-9

Tetracaine hydrochloride  CAS 136-47-0